The Valentine Laboratory: Molecular and Cellular Biomechanics
University of California, Santa Barbara


Publications

  1. Michael T. Woodside and Megan T. Valentine. “Single-molecule manipulation using optical traps,” in Handbook of Single-Molecule Biophysics, eds. Peter Hinterdorfer and Antoine Van Oijen. New York, NY: Springer. In press.

  2. Megan T. Valentine*, Nicholas R. Guydosh*, Braulio Gutiérrez-Medina*, Adrian N. Fehr*, Johan O. Andreasson*, and Steven M. Block. “Precision steering of an optical trap by electro-optic deflection,” Optics Letters. 33 599-601 (2008). (PubMed).

  3. Megan T. Valentine and Susan P. Gilbert (2007) “To step or not to step? How biochemistry influence processivity in kinesin and Eg5,” Current Opinion in Cell Biology 19 75 (PubMed).

  4. Polly M. Fordyce*, Megan T. Valentine*, and Steven M. Block. 2007. "Advances in surface-based assays for single molecules" in Single-Molecule Techniques: A Laboratory Manual, eds. Paul Selvin and Taekjip Ha. Woodbury, NY: Cold Spring Harbor Laboratory Press.

  5. Megan T. Valentine, Polly M. Fordyce, Steven M. Block (2006) “Eg5 steps it up!” Cell Division 1 31 (PubMed).

  6. Megan T. Valentine*, Polly M. Fordyce*, Troy C. Krzysiak, Susan P. Gilbert, Steven M. Block (2006) “Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro,” Nature Cell Biology 8 470 (PubMed).

  7. M. T. Valentine, Z. E. Perlman, T. J. Mitchison, and D. A. Weitz (2005) “Mechanical properties of Xenopus egg cytoplasmic extracts,” Biophysical Journal 88 680 (PubMed).

  8. M. L. Gardel, M. T. Valentine, and D. A. Weitz. 2005. "Microrheology" in Microscale Diagnostic Techniques, ed. Kenny Breuer. New York: Springer-Verlag.

  9. M. T. Valentine, Z. E. Perlman, M. L. Gardel, J. H. Shin, P. Matsudaira, T. J. Mitchison, and D. A. Weitz (2004) “Multiple particle tracking measurements of biomaterials: Effects of colloid surface chemistry,” Biophysical Journal 86 4004 (PubMed).

  10. I. Y. Wong, M. L. Gardel, David R. Reichman, Eric R. Weeks, M. T. Valentine, A. R. Bausch, D. A. Weitz (2004) “Anomalous diffusion probes microstructure dynamics of entangled F-actin networks,” Physical Review Letters 92 178101 (PubMed).

  11. M. L. Gardel, M. T. Valentine, J. C. Crocker, A. R. Bausch, and D. A. Weitz (2003) “Microrheology of entangled F-actin solutions,” Physical Review Letters 91 158302 (PubMed).

  12. Vernita D. Gordon, M. T. Valentine, M. L. Gardel, Daniel Andor, Samantha Dennison, Alexei A. Bogdanov, D. A. Weitz, and Thomas S. Deisboeck (2003) “Measuring the mechanical stress induced by a dynamically expanding multicellular tumor system within a three-dimensional in vitro assay,” Experimental Cell Research 289 58 (PubMed).

  13. A. K. Popp, M. T. Valentine, P. D. Kaplan, D. A. Weitz (2003) “Microscopic origins of light scattering in tissue,” Applied Optics 42 2871 (PubMed).

  14. M. T. Valentine, A. K. Popp, P. D. Kaplan, and D. A. Weitz (2001) “Microscope-based static light scattering instrument,” Optics Letters 26 890 (PubMed).

  15. M. T. Valentine, P. D. Kaplan, D. Thota, J. C. Crocker, T. Gisler, R. K. Prud’homme, M. Beck, and D. A. Weitz (2001) “Investigating the microenvironments of inhomogeneous soft materials with multiple particle tracking,” Physical Review E 64 061506 (PubMed).

  16. M. T. Valentine, A. K. Popp, P. D. Kaplan, and D. A. Weitz (2001) “Microscope-based static light scattering instrument enables precise measurements of heterogeneous materials” Optics and Photonics News 12 37.

  17. John C. Crocker, M. T. Valentine, Eric R. Weeks, T. Gisler, P. D. Kaplan, A. G. Yodh, and D. A. Weitz (2000) “Two-point microrheology of inhomogeneous soft materials,” Physical Review Letters 85 888 (PubMed).

  18. A. K. Popp, M. T. Valentine, P. D. Kaplan, and D. A. Weitz (2000) “Light scattering microscope as a tool to investigate scattering heterogeneity in tissue,” Proceedings of the SPIE, Optical Biopsy III Conference, San Jose, CA, Robert R. Alfano, Ed. 3917 22.

  19. M. T. Valentine, L. E. Dewalt, and H. D. Ou-Yang (1996) “Forces on a colloidal particle in a polymer solution: a study using optical tweezers,” Journal of Physics: Condensed Matter (U.K.). 8 9477.

    * indicates equal contribution